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Support for sequencing

Large-scale DNA sequencing

In recognition of the increasing requirement for sequencing in research, large-scale DNA sequencing needs will be assessed as research grant applications in competition with others in normal responsive mode.

There is no special fund or assessment procedure for applications including sequencing.

The Genome Analysis Centre (TGAC) is a national resource that builds on and extends the UK's existing capacity for genomics through sequencing and analysis of animal, plant and microbial genomes. TGAC is committed to working with partners in other institutes and universities and with international centres.

  • Further information about TGAC can be found in the related links section of this page
  • Information about working with TGAC will be made available shortly
  • Scientists interested in undertaking sequencing work can contact TGAC at the e-mail address below

If you wish to include sequencing at TGAC in your grant application you must complete a Technical Assessment Form (TAF) and submit to TGAC for comments and costing, allowing 4 working weeks for it to be processed and returned to you. See the  TGAC website for more information and to download the TAF. Once complete, send your TAF to the TGAC enquiry contact below.

If your grant application includes large-scale or whole genome sequencing you should include the following information, in addition to the standard scientific case for support:

  • a description of the purposes to which the sequence would be put and the scientific benefits to be gained, making clear those which would derive directly from the grant being sought and those which would be dependent on further resource
  • a statement of the UK research user community (where this is wider than the applicants), its international competitiveness, the science for which they would use the resource, and the impact on the wider academic and user community
  • an assessment of the strategic relevance of the activity to the BBSRC mission and any priority areas
  • an indication of other known sequence data on the same or similar organisms, available or proposed, (e.g. in industry or overseas) and why this cannot be used
  • arrangements for the documentation, storage and distribution of the sequence and the capture of resources and data arising from its research use. We require sequence data to be released in accordance with our Data sharing policy (PDF 485KB)
  • arrangements to ensure the awareness of the target user community, and to secure any synergistic benefits from coordinating usage and sharing of data
  • an appropriate project team including necessary data management expertise, and a management or steering committee where the user community is large or involves many institutions or interests
  • applicants must provide evidence that the chosen facility has the appropriate technical capabilities in the sequencing and the data analysis, if TGAC is not providing the sequencing

Very large whole genome sequencing projects are unlikely to be supported outside the context of international collaborations. Contact us for advice on this if needed.

Where no suitable UK academic partner for sequencing can be found, we will consider funding the acquisition of sequence from industrial and/or overseas sources. Your choice of sequencing organisation should be justified in terms of scientific suitability and cost effectiveness by following the guidelines above when completing your application.

Contact

Michael Ball

tel: 01793 413282
fax: 01793 413234