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Responsibility in the use of animals in bioscience research

May 2008

• Responsibility in the use of animals in bioscience research (PDF 1.48MB)

Co-ordinated by the National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs), the Biotechnology and Biological Sciences Research Council (BBSRC), the Department for Environment, Food and Rural Affairs, the Medical Research Council, the Natural Environment Research Council and the Wellcome Trust have produced this document to clarify their expectations with regard to responsibility in the use of vertebrate animals in bioscience research.

ARRIVE guidelines (see external links)

Animal research: reporting of in vivo experiments

The responsibility in the use of animals in bioscience research document also encourages researchers to report animal-based studies in accordance with the ARRIVE Guidelines. These guidelines are intended to improve standards of reporting and ensure that the data from animal experiments can be fully evaluated and utilised. The guidelines have been published in the journal PLoS Biology and seven other journals (see last external link).

Kilkenny C, Browne WJ, Cuthill IC, Emerson M, Altman DG (2010) Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research. PLoS Biol 8(6): e1000412. doi:10.1371/journal.pbio.1000412.

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